Spaca4 Gene Summary [Mouse]
Involved in binding activity of sperm to zona pellucida. Located in inner acrosomal membrane. Orthologous to human SPACA4 (sperm acrosome associated 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spaca4 |
| Official Name | sperm acrosome associated 4 [Source:MGI Symbol;Acc:MGI:1916613] |
| Ensembl ID | ENSMUSG00000070563 |
| Bio databases IDs | |
| Aliases | sperm acrosome associated 4 |
| Synonyms | 1700008E09RIK, LOC687988, SAMP14, sperm acrosome associated 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spaca4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TFP
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- Extracellular Space
- Plasma Membrane
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spaca4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm-egg recognition
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- acrosomal vesicle
- membrane
- extracellular region
- plasma membrane