Cabyr Gene Summary [Rat]

Predicted to enable calcium ion binding activity; enzyme binding activity; and protein domain specific binding activity. Predicted to be involved in sperm capacitation. Predicted to be located in cytosol; nucleoplasm; and sperm flagellum. Predicted to be active in cytoplasm and sperm fibrous sheath. Orthologous to human CABYR (calcium binding tyrosine phosphorylation regulated). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cabyr
Official Name
calcium binding tyrosine phosphorylation regulated [Source:RGD Symbol;Acc:1585413]
Ensembl ID
ENSRNOG00000047436
Bio databases IDs NCBI: 686189 Ensembl: ENSRNOG00000047436
Aliases calcium binding tyrosine phosphorylation regulated
Synonyms 1700016C01Rik, 4933421A18Rik, CABYRa, CABYRc, CABYRc/d, CABYRe, calcium binding tyrosine phosphorylation regulated, CBP86, CT88, FSP-2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cabyr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calcium ion binding
  • enzyme binding
  • protein domain specific binding
  • protein binding
  • DD_R_PKA_DPY30-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hepatocellular carcinoma
  • epithelial cancer
  • liver cancer
  • lung squamous cell carcinoma
  • squamous cell lung cancer
  • lung cancer
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • brain cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • motile cilia
  • sperm end piece
  • flagella
  • cytosol
  • nucleoplasm
  • sperm tail
  • sperm fibrous sheath

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cabyr gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm capacitation
  • epithelial cilium movement

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • motile cilium
  • cytoskeleton
  • cytoplasm
  • cytosol
  • sperm principal piece
  • flagellar fibrous sheath
  • extracellular region
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding
  • SH3 domain binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.