Mrpl16 Gene Summary [Mouse]

Predicted to enable rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL16 (mitochondrial ribosomal protein L16). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl16
Official Name
mitochondrial ribosomal protein L16 [Source:MGI Symbol;Acc:MGI:2137219]
Ensembl ID
ENSMUSG00000024683
Bio databases IDs NCBI: 94063 Ensembl: ENSMUSG00000024683
Aliases mitochondrial ribosomal protein L16
Synonyms 2310039D06Rik, L16mt, mitochondrial ribosomal protein L16, PNAS-111, uL16m
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Ribosomal_L16_L10e
  • Ribosomal protein L16p/L10e

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nonalcoholic fatty liver disease
  • nonalcoholic steatohepatitis
regulated by
role in cell
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl16 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome
  • rRNA binding

Gene-Specific Assays for Results You Can Trust

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