Sfxn2 Gene Summary [Mouse]

Predicted to enable transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Located in mitochondrial inner membrane. Orthologous to human SFXN2 (sideroflexin 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Sfxn2
Official Name
sideroflexin 2 [Source:MGI Symbol;Acc:MGI:2137678]
Ensembl ID
ENSMUSG00000025036
Bio databases IDs NCBI: 94279 Ensembl: ENSMUSG00000025036
Aliases sideroflexin 2
Synonyms F630107H02RIK, LOC100910912, sideroflexin 2, SLC56A2, SLC64A2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sfxn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sideroflexins
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • osteoporosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane
  • mitochondrial outer membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sfxn2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial outer membrane
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • transmembrane transporter activity
  • ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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