R3hdm2 Gene Summary [Mouse]
Predicted to enable nucleic acid binding activity. Predicted to be located in nucleus. Is expressed in cortical plate; dorsal root ganglion; glossopharyngeal ganglion; trigeminal ganglion; and vagus ganglion. Orthologous to human R3HDM2 (R3H domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | R3hdm2 |
| Official Name | R3H domain containing 2 [Source:MGI Symbol;Acc:MGI:1919000] |
| Ensembl ID | ENSMUSG00000025404 |
| Bio databases IDs | |
| Aliases | R3H domain containing 2 |
| Synonyms | 1300003K24Rik, CAG6, KIAA1002, mKIAA1002, PR01365, R3H domain containing 2, RGD1310066 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse R3hdm2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SUZ domain
- R3H
- R3H domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- coronary artery disease
- schizophrenia
- metabolic syndrome X
- insomnia
- gout
- primary central nervous system lymphoma
- primary cancer
- lymphomagenesis
- central nervous system cancer
- systemic juvenile idiopathic arthritis
regulated by
- JUN
- WPMY-1 cells
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse R3hdm2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding