Ubap2l Gene Summary [Mouse]
Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in chromosome and cytoplasmic stress granule. Predicted to be part of PcG protein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in lung epithelium. Orthologous to human UBAP2L (ubiquitin associated protein 2 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ubap2l |
| Official Name | ubiquitin-associated protein 2-like [Source:MGI Symbol;Acc:MGI:1921633] |
| Ensembl ID | ENSMUSG00000042520 |
| Bio databases IDs | |
| Aliases | ubiquitin-associated protein 2-like |
| Synonyms | 3110083O19Rik, 4932431F02RIK, A430103N23Rik, Atp8b2, EP1, KIAA0144, mKIAA0144, NEDLBF, NICE-4, ubiquitin-associated protein 2-like |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ubap2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- RGG/RG motif
- Ubiquitin-associated protein 2
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic facies
- breast cancer
- insomnia
regulates
- insulin
- PRKN
role in cell
- binding
- attachment
- formation
- homeostasis
- assembly
- hyperassembly
- hyperassembly in
- alignment in
- formation in
- alignment
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ubap2l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- stress granule assembly
- binding of sperm to zona pellucida
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasmic stress granule
- cytoplasm
- PcG protein complex
- chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding