Ttc4 Gene Summary [Mouse]
Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Predicted to be involved in defense response to virus; innate immune response; and protein folding. Located in cytoplasm and nucleus. Is expressed in central nervous system; ganglia; olfactory epithelium; renal cortex; and thymus primordium. Orthologous to human TTC4 (tetratricopeptide repeat domain 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ttc4 |
| Official Name | tetratricopeptide repeat domain 4 [Source:MGI Symbol;Acc:MGI:1919604] |
| Ensembl ID | ENSMUSG00000025413 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat domain 4 |
| Synonyms | 2810002P21Rik, CNS1, L62, LOC100129188, tetratricopeptide repeat domain 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ttc4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- CTWD_Cns1-like
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ttc4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- defense response to virus
- protein folding
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- Hsp90 protein binding
- Hsp70 protein binding