Ttc4 Gene Summary [Rat]

Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Predicted to be involved in defense response to virus; innate immune response; and protein folding. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human TTC4 (tetratricopeptide repeat domain 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ttc4
Official Name
tetratricopeptide repeat domain 4 [Source:RGD Symbol;Acc:1308529]
Ensembl ID
ENSRNOG00000042467
Bio databases IDs NCBI: 362556 Ensembl: ENSRNOG00000042467
Aliases tetratricopeptide repeat domain 4
Synonyms 2810002P21Rik, CNS1, L62, LOC100129188, tetratricopeptide repeat domain 4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ttc4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TPR repeat
  • CTWD_Cns1-like
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ttc4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • innate immune response
  • defense response to virus
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • Hsp90 protein binding
  • Hsp70 protein binding

Gene-Specific Assays for Results You Can Trust

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