Fuom Gene Summary [Mouse]

Enables L-fucose mutarotase activity and fucose binding activity. Involved in GDP-L-fucose salvage and fucose metabolic process. Acts upstream of or within female mating behavior; fucosylation; and negative regulation of neuron differentiation. Is active in cytosol. Orthologous to human FUOM (fucose mutarotase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fuom
Official Name
fucose mutarotase [Source:MGI Symbol;Acc:MGI:1916314]
Ensembl ID
ENSMUSG00000025466
Bio databases IDs NCBI: 69064 Ensembl: ENSMUSG00000025466
Aliases fucose mutarotase
Synonyms C10orf125, FucM, fucose mutarotase, Fucose Operon, FUCU, Le51, LOC100911225, RGD1311186
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fuom often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • carbohydrate racemase or epimerase
  • fucose binding
  • enzyme
  • RbsD / FucU transport protein family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • L-triiodothyronine
regulates
  • fucose
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fuom gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • fucosylation
  • fucose metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • racemase and epimerase activity, acting on carbohydrates and derivatives
  • fucose binding

Gene-Specific Assays for Results You Can Trust

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