Dusp23 Gene Summary [Mouse]

Predicted to enable protein tyrosine phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in cilium assembly and dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human DUSP23 (dual specificity phosphatase 23). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Dusp23
Official Name
dual specificity phosphatase 23 [Source:MGI Symbol;Acc:MGI:1915690]
Ensembl ID
ENSMUSG00000026544
Bio databases IDs NCBI: 68440 Ensembl: ENSMUSG00000026544
Aliases dual specificity phosphatase 23
Synonyms 1300005N15Rik, dual specificity phosphatase 23, DUSP25, LDP-3, LOC100048558, LOC100366094, MOSP, VHZ
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dusp23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Dual specificity phosphatase, catalytic domain
  • Protein tyrosine phosphatase, catalytic domain, undefined specificity
  • protein tyrosine/serine/threonine phosphatase
  • phosphatase
  • protein binding
  • PTP_DSP_cys
  • Protein tyrosine phosphatase, catalytic domain motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic lymphocytic leukemia
regulated by
regulates
  • ethylene glycol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dusp23 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis
  • dephosphorylation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein tyrosine phosphatase activity
  • phosphatase activity
  • protein tyrosine/serine/threonine phosphatase activity
  • myosin phosphatase activity

Gene-Specific Assays for Results You Can Trust

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