Tm9sf2 Gene Summary [Mouse]
Predicted to be involved in protein localization to membrane; regulation of heparan sulfate proteoglycan biosynthetic process; and sphingolipid metabolic process. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Is expressed in several structures, including brain; cranium; eye; hemolymphoid system gland; and liver. Orthologous to human TM9SF2 (transmembrane 9 superfamily member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tm9sf2 |
| Official Name | transmembrane 9 superfamily member 2 [Source:MGI Symbol;Acc:MGI:1915309] |
| Ensembl ID | ENSMUSG00000025544 |
| Bio databases IDs | |
| Aliases | transmembrane 9 superfamily member 2 |
| Synonyms | 1500001N15Rik, D14Ertd64e, Lnc-PCIR, P76, transmembrane 9 superfamily member 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tm9sf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Endomembrane protein 70
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- endosomal membrane fractions
- pH resistant lipid raft fraction
- Nucleus
- endosomes
- Golgi Apparatus
- Golgi membrane
- endosomal membrane
- membrane rafts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tm9sf2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization in membrane
- ceramide metabolic process
- glycosphingolipid biosynthetic process
- regulation of heparan sulfate proteoglycan biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endosome
- extracellular vesicular exosome
- microtubule organizing center
- membrane
- endosome membrane
- Golgi apparatus
- plasma membrane