Tspan17 Gene Summary [Mouse]

Enables enzyme binding activity. Involved in protein maturation. Predicted to be active in plasma membrane. Is expressed in brain; ganglia; neural retina; and ventral grey horn. Orthologous to human TSPAN17 (tetraspanin 17). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tspan17
Official Name
tetraspanin 17 [Source:MGI Symbol;Acc:MGI:1921507]
Ensembl ID
ENSMUSG00000025875
Bio databases IDs NCBI: 74257 Ensembl: ENSMUSG00000025875
Aliases tetraspanin 17
Synonyms 2210021G21RIK, AI047581, FBX23, FBXO23, GHB-R, MGC14859, tetraspanin 17, TM4SF17
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tspan17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tetraspanin_LEL
  • enzyme binding
  • enzyme
  • Tetraspanin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
role in cell
  • expression in
  • transmigration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tspan17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • establishment of protein localization to organelle
  • regulation of membrane protein ectodomain proteolysis

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • enzyme binding

Gene-Specific Assays for Results You Can Trust

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