Unc50 Gene Summary [Mouse]

Predicted to enable RNA binding activity. Predicted to be involved in protein localization to cell surface. Located in Golgi apparatus. Orthologous to human UNC50 (unc-50 inner nuclear membrane RNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Unc50
Official Name
unc-50 homolog [Source:MGI Symbol;Acc:MGI:1914637]
Ensembl ID
ENSMUSG00000026111
Bio databases IDs NCBI: 67387 Ensembl: ENSMUSG00000026111
Aliases unc-50 homolog
Synonyms 1110002A21RIK, GMH1, HSD23, PDLs22, unc-50 homolog, unc-50 inner nuclear membrane RNA binding protein, UNCL, URP
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Unc50 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UNC-50 family
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diverticular disease
regulated by
regulates
  • GBF1
  • stxB2
  • Shiga toxin 2
role in cell
  • degradation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Golgi Apparatus
  • inner nuclear membrane
  • cis Golgi cisternae

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Unc50 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein localization at cell surface

Cellular Component

Where in the cell the gene product is active
  • nuclear inner membrane
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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