Tepsin Gene Summary [Mouse]

Predicted to be located in coated vesicle membrane. Predicted to be extrinsic component of organelle membrane. Predicted to be part of AP-4 adaptor complex. Predicted to be active in trans-Golgi network membrane. Orthologous to human TEPSIN (TEPSIN adaptor related protein complex 4 accessory protein). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tepsin
Official Name
TEPSIN, adaptor related protein complex 4 accessory protein [Source:MGI Symbol;Acc:MGI:1926027]
Ensembl ID
ENSMUSG00000025377
Bio databases IDs NCBI: 78777 Ensembl: ENSMUSG00000025377
Aliases TEPSIN, adaptor related protein complex 4 accessory protein
Synonyms 2410002I01Rik, C17orf56, ENTHD2, RGD1307410, TEPSIN adaptor related protein complex 4 accessory protein, TEPSIN, adaptor related protein complex 4 accessory protein
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tepsin often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • VHS, ENTH and ANTH domain superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • frontotemporal dementia
regulated by
regulates
role in cell
  • co-precipitation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytoplasmic vesicle membrane
  • intracellular membrane-bounded organelle
  • Cytoplasm
  • cellular membrane
  • trans Golgi network

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tepsin gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • intracellular membrane-bounded organelle
  • cytosol
  • coated vesicle membrane
  • organelle membrane
  • trans-Golgi network membrane
  • extrinsic to organelle membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.