Efcab2 Gene Summary [Mouse]
Enables calcium ion binding activity. Located in sperm principal piece. Is expressed in several structures, including endocrine gland; forelimb bud; genitourinary system; lung; and nervous system. Orthologous to human EFCAB2 (EF-hand calcium binding domain 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Efcab2 |
| Official Name | EF-hand calcium binding domain 2 [Source:MGI Symbol;Acc:MGI:1915476] |
| Ensembl ID | ENSMUSG00000026495 |
| Bio databases IDs | |
| Aliases | EF-hand calcium binding domain 2 |
| Synonyms | 1700073K01RIK, CFAP200, D830011E08RIK, DRC8, EF-hand calcium binding domain 2, LOC102550369, RGD1308593 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Efcab2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand domain
- EF-hand domain pair
- calcium ion binding
- EFh
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Efcab2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
- sperm principal piece
Molecular Function
What the gene product does at the molecular level
- calcium ion binding