Iqcn Gene Summary [Mouse]
Involved in spermatid development. Acts upstream of or within single fertilization and sperm flagellum assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in spermatogenic failure 78. Orthologous to human IQCN (IQ motif containing N). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Iqcn |
| Official Name | IQ motif containing N [Source:MGI Symbol;Acc:MGI:3708784] |
| Ensembl ID | ENSMUSG00000110622 |
| Bio databases IDs | |
| Aliases | IQ motif containing N |
| Synonyms | AC162446.6, Gm16486, IQ motif containing N, KIAA1683, LOC306346, SPGF78 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Iqcn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Family of unknown function (DUF5585)
- Calmodulin-binding motif
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- protein binding
- IQ calmodulin-binding motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Iqcn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatid development
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding