Tnni2

Predicted to enable troponin T binding activity. Predicted to contribute to actin binding activity. Predicted to be involved in cardiac muscle contraction; positive regulation of DNA-templated transcription; and skeletal muscle contraction. Predicted to be located in nucleus. Predicted to be part of troponin complex. Is expressed in several structures, including alimentary system; eyelid epithelium; heart; hindlimb muscle; and integumental system. Used to study distal arthrogryposis. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita and distal arthrogryposis type 2B1. Orthologous to human TNNI2 (troponin I2, fast skeletal type). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tnni2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Tnni2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tnni2 gene, providing context for its role in the cell.