Ccdc34 Gene Summary [Mouse]
Involved in spermatogenesis. Located in sperm midpiece. Used to study spermatogenic failure. Human ortholog(s) of this gene implicated in spermatogenic failure 76. Orthologous to human CCDC34 (coiled-coil domain containing 34). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccdc34 |
| Official Name | coiled-coil domain containing 34 [Source:MGI Symbol;Acc:MGI:1915451] |
| Ensembl ID | ENSMUSG00000027160 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 34 |
| Synonyms | 2810027O19Rik, 4930522P10Rik, coiled-coil domain containing 34, L15, LOC81023, NY-REN-41, RAMA3, RGD1560583, SPGF76 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccdc34 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Coiled-coil domain-containing protein 3
- protein binding
- zDHHC ankyrin repeat binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- fulvestrant
disease
- colorectal cancer
- spermatogenic failure 76
- lung adenocarcinoma formation
- EGFR mutation positive adenocarcinoma of the lung
- EGFR mutation positive non-small cell lung cancer
- EGFR expression positive non-squamous non-small cell lung cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sperm midpiece
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccdc34 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
Cellular Component
Where in the cell the gene product is active
- sperm midpiece