Fam76b Gene Summary [Mouse]

Predicted to enable RNA binding activity. Involved in negative regulation of macrophage activation. Predicted to be active in nuclear speck. Is expressed in esophagus and heart ventricle. Orthologous to human FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Fam76b
Official Name
family with sequence similarity 76, member B [Source:MGI Symbol;Acc:MGI:1920076]
Ensembl ID
ENSMUSG00000037808
Bio databases IDs NCBI: 72826 Ensembl: ENSMUSG00000037808
Aliases family with sequence similarity 76, member B
Synonyms 2810485I05Rik, family with sequence similarity 76 member B, family with sequence similarity 76, member B, RGD1311077
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam76b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FAM76 protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • productive infection by HIV-1
regulated by
regulates
role in cell
  • activation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam76b gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nuclear speck

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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