Commd9 Gene Summary [Mouse]

Acts upstream of or within cholesterol homeostasis. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and skeleton. Orthologous to human COMMD9 (COMM domain containing 9). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Commd9
Official Name
COMM domain containing 9 [Source:MGI Symbol;Acc:MGI:1923751]
Ensembl ID
ENSMUSG00000027163
Bio databases IDs NCBI: 76501 Ensembl: ENSMUSG00000027163
Aliases COMM domain containing 9
Synonyms 1810029F08Rik, C11orf55, COMM domain containing 9, HSPC166, LINC00610
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Commd9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • COMM domain
  • protein binding
  • Commd

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cardiovascular disorder
regulated by
  • pevonedistat
  • CSN5i-3
  • sodium arsenite
regulates
role in cell
  • expression in
  • morphology
  • accumulation in
  • signaling in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • secretory granule lumen
  • ficolin-1-rich granule lumen
  • Extracellular Space
  • Golgi Apparatus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Commd9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sodium ion transport
  • cholesterol homeostasis

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • secretory granule lumen
  • Golgi apparatus
  • extracellular region
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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