Commd6 Gene Summary [Mouse]
Predicted to enable NF-kappaB binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within negative regulation of NF-kappaB transcription factor activity. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human COMMD6 (COMM domain containing 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Commd6 |
| Official Name | COMM domain containing 6 [Source:MGI Symbol;Acc:MGI:1913450] |
| Ensembl ID | ENSMUSG00000075486 |
| Bio databases IDs | |
| Aliases | COMM domain containing 6 |
| Synonyms | 1110059J08Rik, 1700063H17RIK, Acrg, COMM domain containing 6, RGD1560745 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Commd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NF-kappaB binding
- COMM domain
- protein binding
- Commd
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Commd6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of NF-kappaB transcription factor activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- NF-kappaB binding
- protein binding