Wdr76 Gene Summary [Mouse]
Predicted to enable DNA binding activity and enzyme binding activity. Predicted to be involved in DNA damage response and regulation of DNA damage checkpoint. Predicted to be located in heterochromatin and site of DNA damage. Predicted to be active in nucleus. Orthologous to human WDR76 (WD repeat domain 76). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr76 |
| Official Name | WD repeat domain 76 [Source:MGI Symbol;Acc:MGI:1926186] |
| Ensembl ID | ENSMUSG00000027242 |
| Bio databases IDs | |
| Aliases | WD repeat domain 76 |
| Synonyms | 5830411K18Rik, 6030457D09, CDW14, CMR1, LOC688052, RGD1309616, WD repeat domain 76 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr76 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- heterochromatin
- nuclear scaffolds
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr76 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of DNA damage checkpoint
- response to DNA damage stimulus
Cellular Component
Where in the cell the gene product is active
- nucleus
- heterochromatin
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- enzyme binding