WDR76 Gene Summary [Human]
Enables enzyme binding activity. Involved in cellular response to DNA damage stimulus. Located in heterochromatin; nucleus; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | WDR76 |
| Official Name | WD repeat domain 76 [Source:HGNC Symbol;Acc:HGNC:25773] |
| Ensembl ID | ENSG00000092470 |
| Bio databases IDs | |
| Aliases | WD repeat domain 76 |
| Synonyms | 5830411K18Rik, 6030457D09, CDW14, CMR1, LOC688052, RGD1309616, WD repeat domain 76 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WDR76 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- heterochromatin
- nuclear scaffolds
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human WDR76 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of DNA damage checkpoint
- response to DNA damage stimulus
Cellular Component
Where in the cell the gene product is active
- nucleus
- heterochromatin
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- enzyme binding