Cd93 Gene Summary [Mouse]
Predicted to enable complement component C1q complex binding activity. Predicted to be involved in cell-cell adhesion. Located in cell surface; cytoplasmic vesicle; and plasma membrane. Is expressed in blood vessel and early conceptus. Orthologous to human CD93 (CD93 molecule). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd93 |
| Official Name | CD93 antigen [Source:MGI Symbol;Acc:MGI:106664] |
| Ensembl ID | ENSMUSG00000027435 |
| Bio databases IDs | |
| Aliases | CD93 antigen |
| Synonyms | 6030404G09Rik, AA4.1, C1QR, C1QR1, C1qRP, C1qR(P), CD93 antigen, CD93 molecule, CDw93, dJ737E23.1, ECSM3, gC1qR, Ly68, MXRA4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd93 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Complement Clr-like EGF-like
- signaling receptor activity
- binding protein
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- EGF domain
- protein binding
- Coagulation Factor Xa inhibitory site
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- glioblastoma
- edema
- autism-like behavioral deficit
- venous thromboembolism
- metabolic syndrome X
- glioblastoma cancer
- infection by Zaire ebolavirus
role in cell
- phosphorylation in
- expression in
- production in
- morphology
- cellular infiltration by
- activity
- phagocytosis
- phagocytosis by
- recruitment
- astrogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cell surface
- apical compartment
- cellular membrane
- vesicles
- secretory granule membrane
- tertiary granule membrane
- specific granule membrane
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd93 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phagocytosis
- macrophage activation
Cellular Component
Where in the cell the gene product is active
- secretory granule membrane
- plasma membrane
- tertiary granule membrane
- specific granule membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- signaling receptor activity
- complement component C1q binding
- carbohydrate binding