Cst8 Gene Summary [Mouse]
Predicted to enable cysteine-type endopeptidase inhibitor activity. Located in cell surface; cytoplasm; and extracellular region. Is expressed in epididymis; gonad; and urogenital ridge. Orthologous to human CST8 (cystatin 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cst8 |
| Official Name | cystatin 8 (cystatin-related epididymal spermatogenic) [Source:MGI Symbol;Acc:MGI:107161] |
| Ensembl ID | ENSMUSG00000027442 |
| Bio databases IDs | |
| Aliases | cystatin 8 (cystatin-related epididymal spermatogenic) |
| Synonyms | CRES, Cst-rs1, CTES5, cystatin 8, cystatin 8 (cystatin-related epididymal spermatogenic) |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cst8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CY
- cysteine protease inhibitor activity
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- cell surface
- secretory granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cst8 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- extracellular region
- cell surface
Molecular Function
What the gene product does at the molecular level
- cysteine-type endopeptidase inhibitor activity