Wdr26 Gene Summary [Mouse]
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of GID complex. Orthologous to human WDR26 (WD repeat domain 26). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr26 |
| Official Name | WD repeat domain 26 [Source:MGI Symbol;Acc:MGI:1923825] |
| Ensembl ID | ENSMUSG00000038733 |
| Bio databases IDs | |
| Aliases | WD repeat domain 26 |
| Synonyms | 1600024A01Rik, AU044014, CDW2, GID7, LOC114227, MIP2, RGD1565589, SKDEAS, WD repeat domain 26 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD-like repeat
- LisH-like dimerization domain
- WD40 repeats
- WD domain, G-beta repeat
- C-terminal to LisH motif
- WD40
- LisH-CTLH domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hereditary disorder
- Skraban-Deardorff syndrome
- idiopathic scoliosis
- mental retardation
role in cell
- chemotaxis
- migration
- activation in
- apoptosis
- signaling in
- binding in
- homing
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr26 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- ubiquitin ligase complex
- cytoplasm
- mitochondrion
- cytosol
- GID complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding