B4galt3 Gene Summary [Mouse]
Predicted to enable galactosyltransferase activity. Predicted to be involved in galactosylceramide biosynthetic process and glycosylation. Predicted to be located in cytosol. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human B4GALT3 (beta-1,4-galactosyltransferase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | B4galt3 |
| Official Name | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 [Source:MGI Symbol;Acc:MGI:1928767] |
| Ensembl ID | ENSMUSG00000052423 |
| Bio databases IDs | |
| Aliases | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 |
| Synonyms | 9530061M23Rik, Beta 1,4- Galactosyl Transferase3, beta4Gal-T3, ESTM26, ESTM6, R74981, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3, UDP-Gal:betaGlcNAc β 1,4-galactosyltransferase, polypeptide 3, β 1,4- Galactosyl Transferase3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B4galt3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
- galactosyltransferase
- N-terminal domain of galactosyltransferase
- N-terminal region of glycosyl transferase group 7
- enzyme
- N-acetyllactosamine synthase
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial uterine cancer
- renal clear cell adenocarcinoma
- renal clear cell cancer
- lung squamous cell carcinoma
- squamous cell lung cancer
- uterine corpus endometrioid carcinoma
- uterine corpus cancer
- endometrioid cancer
- breast adenocarcinoma
- colorectal carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- cytosol
- Golgi membrane
- trans Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse B4galt3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycosylation
- carbohydrate metabolic process
- protein glycosylation
- galactosylceramide biosynthetic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- Golgi cisterna membrane
- cytosol
- Golgi apparatus
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
- metal ion binding
- N-acetyllactosamine synthase activity
- galactosyltransferase activity