Rprd2 Gene Summary [Mouse]

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be part of transcription preinitiation complex. Is expressed in several structures, including blastocyst; cerebral cortex; early embryo; and extraembryonic component. Orthologous to human RPRD2 (regulation of nuclear pre-mRNA domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rprd2
Official Name
regulation of nuclear pre-mRNA domain containing 2 [Source:MGI Symbol;Acc:MGI:1922387]
Ensembl ID
ENSMUSG00000028106
Bio databases IDs NCBI: 75137 Ensembl: ENSMUSG00000028106
Aliases regulation of nuclear pre-mRNA domain containing 2
Synonyms 2810036A19Rik, 4930535B03Rik, 6720469I21RIK, BB077382, HSPC099, KIAA0460, mKIAA0460, regulation of nuclear pre-mRNA domain containing 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rprd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • VHS, ENTH and ANTH domain superfamily
  • CID domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • major depression
  • headache
  • coronary artery disease
  • osteoarthritis
  • pain
  • insomnia
  • atopic dermatitis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rprd2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mRNA 3'-end processing

Cellular Component

Where in the cell the gene product is active
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA polymerase II core binding

Gene-Specific Assays for Results You Can Trust

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