Spaca1 Gene Summary [Mouse]
Acts upstream of or within acrosome assembly. Located in acrosomal membrane. Human ortholog(s) of this gene implicated in spermatogenic failure 85. Orthologous to human SPACA1 (sperm acrosome associated 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spaca1 |
| Official Name | sperm acrosome associated 1 [Source:MGI Symbol;Acc:MGI:1914902] |
| Ensembl ID | ENSMUSG00000028264 |
| Bio databases IDs | |
| Aliases | sperm acrosome associated 1 |
| Synonyms | 1700124L11Rik, 4930540L03RIK, RGD1560284, SAMP32, sperm acrosome associated 1, SPGF85 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spaca1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spaca1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acrosome assembly
Cellular Component
Where in the cell the gene product is active
- acrosomal membrane
- inner acrosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding