Ap1m2 Gene Summary [Mouse]
Predicted to enable clathrin adaptor activity. Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be part of AP-1 adaptor complex. Predicted to be active in clathrin-coated vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human AP1M2 (adaptor related protein complex 1 subunit mu 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Ap1m2 |
| Official Name | adaptor protein complex AP-1, mu 2 subunit [Source:MGI Symbol;Acc:MGI:1336974] |
| Ensembl ID | ENSMUSG00000003309 |
| Bio databases IDs | |
| Aliases | adaptor protein complex AP-1, mu 2 subunit |
| Synonyms | adaptor protein complex AP-1, mu 2 subunit, adaptor related protein complex 1 subunit mu 2, AP1-mu2, D9Ertd818e, HSMU1B, [m]1B, MU-1B, mu2, RGD1561490 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ap1m2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AP_MHD_Cterm
- Adaptor complexes medium subunit family
- protein binding
- Longin-like domains
- transporter
Pathways
Biological processes and signaling networks where the Ap1m2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- intracellular membrane-bounded organelle
- perinuclear region
- endosomes
- Golgi Apparatus
- cytosol
- Golgi membrane
- trans Golgi network
- lysosome membrane
- recycling endosomes
- clathrin-coated vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ap1m2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting
- vesicle-mediated transport
- vesicle targeting
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- intracellular membrane-bounded organelle
- AP-1 adaptor complex
- cytosol
- Golgi membrane
- clathrin-coated vesicle
- lysosomal membrane
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- clathrin adaptor activity