Bspry Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cell leading edge and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including cornea epithelium; genitourinary system; gut; nose; and salivary gland primordium. Orthologous to human BSPRY (B-box and SPRY domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bspry |
| Official Name | B-box and SPRY domain containing [Source:MGI Symbol;Acc:MGI:2177191] |
| Ensembl ID | ENSMUSG00000028392 |
| Bio databases IDs | |
| Aliases | B-box and SPRY domain containing |
| Synonyms | B-box and SPRY domain containing, LOC64027 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bspry often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- B-box-type zinc finger superfamily
- SPRY domain
- protein binding
- associated with SPRY domains
- SPRY-associated domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- cell membrane leading edge
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bspry gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- calcium ion transport
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytoplasm
- cell leading edge
- membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding