Cyp4b1 Gene Summary [Mouse]
Predicted to enable heterocyclic compound binding activity. Predicted to be involved in biphenyl metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including liver; lung; male reproductive gland or organ; metanephros; and spleen. Orthologous to human CYP4B1 (cytochrome P450 family 4 subfamily B member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Cyp4b1 |
| Official Name | cytochrome P450, family 4, subfamily b, polypeptide 1 [Source:MGI Symbol;Acc:MGI:103225] |
| Ensembl ID | ENSMUSG00000028713 |
| Bio databases IDs | |
| Aliases | cytochrome P450, family 4, subfamily b, polypeptide 1 |
| Synonyms | CYP4B, CYPIVB1, cytochrome P450 family 4 subfamily B member 1, cytochrome P450, family 4, subfamily b, polypeptide 1, P-450HP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cyp4b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome P450 (CYP) superfamily
- Cytochrome P450
- oxygen binding
- binding protein
- unspecific monooxygenase
- monooxygenase
- enzyme
Pathways
Biological processes and signaling networks where the Cyp4b1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung cancer
- chronic obstructive pulmonary disease
- COVID-19
- chronic periodontal disease
- oral submucous fibrosis
regulates
- octanoic acid
- decanoic acid
- heme
- lauric acid
- pelargonic acid
- diphenyl
- fatty acid
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- detergent resistant lipid raft fraction
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cyp4b1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- biphenyl metabolic process
- fatty acid metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- oxygen binding
- iron ion binding
- aromatase activity
- monooxygenase activity
- heme binding