Rhd Gene Summary [Mouse]
Predicted to enable ammonium channel activity. Acts upstream of or within ammonium transmembrane transport; erythrocyte development; and multicellular organismal-level iron ion homeostasis. Located in membrane. Is expressed in several structures, including gonad; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in Rh isoimmunization. Orthologous to several human genes including RHD (Rh blood group D antigen). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rhd |
| Official Name | Rh blood group, D antigen [Source:MGI Symbol;Acc:MGI:1202882] |
| Ensembl ID | ENSMUSG00000028825 |
| Bio databases IDs | |
| Aliases | Rh blood group, D antigen |
| Synonyms | CD240CE, RH, Rh30, RH30A, Rh4, Rh blood group CcEe antigens, Rh blood group, D antigen, RHC, RHCe(152N), Rhced, RHD, RHE, Rhesus C/E antigens, RhIVb(J), RHIXB, Rhl1, RHNA, RHPI, Rh polypeptide 1, RhVI, RhVIII, SLC42A4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rhd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transporter
- Ammonium Transporter Family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- cell surface
- cellular membrane
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rhd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ammonium transmembrane transport
- ammonia homeostasis
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ammonium transmembrane transporter activity