Tmem222 Gene Summary [Mouse]

Predicted to be located in dendrite. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system. Orthologous to human TMEM222 (transmembrane protein 222). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tmem222
Official Name
transmembrane protein 222 [Source:MGI Symbol;Acc:MGI:1098568]
Ensembl ID
ENSMUSG00000028857
Bio databases IDs NCBI: 52174 Ensembl: ENSMUSG00000028857
Aliases transmembrane protein 222
Synonyms 5730406H10Rik, C1orf160, D4Ertd196e, NEDMOSBA, RGD1304793, transmembrane protein 222
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem222 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein of unknown function (DUF778)
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neurodevelopmental disorder with motor and speech delay and behavioral abnormalities
regulated by
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem222 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.