Bcl7b Gene Summary [Mouse]
Predicted to be involved in several processes, including positive regulation of stem cell population maintenance; regulation of cell cycle process; and regulation of nucleobase-containing compound metabolic process. Part of SWI/SNF complex. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and skin. Orthologous to human BCL7B (BAF chromatin remodeling complex subunit BCL7B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bcl7b |
| Official Name | B cell CLL/lymphoma 7B [Source:MGI Symbol;Acc:MGI:1332238] |
| Ensembl ID | ENSMUSG00000029681 |
| Bio databases IDs | |
| Aliases | B cell CLL/lymphoma 7B |
| Synonyms | BAF chromatin remodeling complex subunit BCL7B, B cell CLL/lymphoma 7B, LOC100040069, LOC100048278, SMARCJ2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bcl7b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BCL7, N-terminal conserver region
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bcl7b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of mitotic metaphase/anaphase transition
- positive regulation of cell proliferation
- regulation of nucleotide-excision repair
- regulation of transcription from RNA polymerase II promoter
- chromatin remodeling
- negative regulation of cell differentiation
- apoptotic process
- cell differentiation
- Wnt receptor signaling pathway
- regulation of G1/S transition of mitotic cell cycle
- positive regulation of double-strand break repair
- regulation of G0 to G1 transition
Cellular Component
Where in the cell the gene product is active
- SWI/SNF complex
- chromatin
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding