Tsc22d4 Gene Summary [Mouse]
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3; MIM 300506) (Kester et al., 1999 [PubMed 10488076]; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | Tsc22d4 |
| Official Name | TSC22 domain family, member 4 [Source:MGI Symbol;Acc:MGI:1926079] |
| Ensembl ID | ENSMUSG00000029723 |
| Bio databases IDs | |
| Aliases | TSC22 domain family, member 4 |
| Synonyms | 0610009M14RIK, 1700023B23Rik, AI415410, LOC100910713, LOC102550456, LOC686226, SPACDR, T22D4, THG-1, Thg-1pit, TILZ2, TSC22 domain family member 4, TSC22 domain family, member 4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tsc22d4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TSC box
- transcription regulator
- DNA binding domain
- TSC-22/dip/bun family
- leucine zipper domain
- ETGE motif
- ZIP_TSC22D-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- acrosome
- synapse
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tsc22d4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- neuron homeostasis
- negative regulation of transcription, DNA-dependent
- glucose homeostasis
- response to osmotic stress
Cellular Component
Where in the cell the gene product is active
- dendrite
- nucleus
- cytoplasm
- synapse
Molecular Function
What the gene product does at the molecular level
- protein binding