Mrpl53 Gene Summary [Mouse]
Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; pancreas epithelium; retina; and submandibular gland primordium. Orthologous to human MRPL53 (mitochondrial ribosomal protein L53). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrpl53 |
| Official Name | mitochondrial ribosomal protein L53 [Source:MGI Symbol;Acc:MGI:1915749] |
| Ensembl ID | ENSMUSG00000030037 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L53 |
| Synonyms | 1110007K17Rik, L53MT, LOC103692169, mitochondrial ribosomal protein L53, mL53 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl53 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- 39S ribosomal protein L53/MRP-L53
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl53 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding