Emp1 Gene Summary [Mouse]
Predicted to be involved in apoptotic process and bleb assembly. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; heart valve; and nervous system. Orthologous to human EMP1 (epithelial membrane protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Emp1 |
| Official Name | epithelial membrane protein 1 [Source:MGI Symbol;Acc:MGI:107941] |
| Ensembl ID | ENSMUSG00000030208 |
| Bio databases IDs | |
| Aliases | epithelial membrane protein 1 |
| Synonyms | CL-20, ENP1MR, epithelial membrane protein 1, I-8-09, TMP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Emp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PMP-22/EMP/MP20/Claudin family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- epithelial neoplasia
- cancer
- adenoma formation
- metastasis
- glioblastoma cancer
- central nervous system cancer
- head and neck cancer
- head and neck neoplasia
- glioma cancer
role in cell
- phosphorylation in
- activation in
- apoptosis
- proliferation
- cell death
- survival
- formation
- invasion
- condensation
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Emp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- bleb assembly
- apoptotic process
- epidermis development
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding