Dbx1

Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within regulation of transcription by RNA polymerase II and ventral spinal cord interneuron specification. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; future brain; head mesenchyme; urogenital ridge; and vertebral axis musculature. Orthologous to human DBX1 (developing brain homeobox 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dbx1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Dbx1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dbx1 gene, providing context for its role in the cell.