Haus7 Gene Summary [Mouse]

Predicted to enable microtubule minus-end binding activity and thioesterase binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in microtubule cytoskeleton; nucleolus; and plasma membrane. Predicted to be part of HAUS complex. Orthologous to human HAUS7 (HAUS augmin like complex subunit 7). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Haus7
Official Name
HAUS augmin-like complex, subunit 7 [Source:MGI Symbol;Acc:MGI:1920988]
Ensembl ID
ENSMUSG00000031371
Bio databases IDs NCBI: 73738 Ensembl: ENSMUSG00000031371
Aliases HAUS augmin-like complex, subunit 7
Synonyms 1110020L19Rik, HAUS augmin like complex subunit 7, HAUS augmin-like complex, subunit 7, RGD1562991, UCHL5IP, UIP1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Haus7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • alopecia
regulated by
  • MEL S3
  • lenalidomide
  • PCM1
  • IND S7
role in cell
  • assembly
  • misalignment in
  • misalignment
  • cycling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • basal bodies
  • centrosome
  • cytosol
  • nucleoli
  • spindle fibers

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Haus7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • spindle assembly
  • centrosome cycle
  • regulation of microtubule nucleation

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytosol
  • HAUS complex
  • nucleolus
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • microtubule minus-end binding
  • thioesterase binding

Gene-Specific Assays for Results You Can Trust

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