Haus8 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in mitotic spindle microtubule. Predicted to be part of HAUS complex. Predicted to be active in centrosome; cytoplasm; and nuclear microtubule. Orthologous to human HAUS8 (HAUS augmin like complex subunit 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Haus8 |
| Official Name | 4HAUS augmin-like complex, subunit 8 [Source:MGI Symbol;Acc:MGI:1923728] |
| Ensembl ID | ENSMUSG00000035439 |
| Bio databases IDs | |
| Aliases | 4HAUS augmin-like complex, subunit 8 |
| Synonyms | 2410004L22Rik, 4HAUS augmin-like complex, subunit 8, DGT4, HAUS augmin like complex subunit 8, HAUS augmin-like complex, subunit 8, HICE1, NY-SAR-48, RGD1311565 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Haus8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypertension
- asthma
role in cell
- cell death
- formation
- cycling
- formation in
- interaction in
- misalignment in
- nucleation in
- interaction
- misalignment
- assembly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- cytosol
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Haus8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle assembly
- centrosome cycle
- regulation of microtubule nucleation
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- spindle pole
- nuclear microtubule
- cytosol
- HAUS complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding