Haus6 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in centrosome. Predicted to be part of HAUS complex. Predicted to be active in mitotic spindle microtubule. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human HAUS6 (HAUS augmin like complex subunit 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Haus6 |
| Official Name | HAUS augmin-like complex, subunit 6 [Source:MGI Symbol;Acc:MGI:1923389] |
| Ensembl ID | ENSMUSG00000038047 |
| Bio databases IDs | |
| Aliases | HAUS augmin-like complex, subunit 6 |
| Synonyms | 6230416J20Rik, 9830144E06, D4Ertd27e, Dgt6, FAM29A, HAUS augmin like complex subunit 6, HAUS augmin-like complex, subunit 6, mKIAA1574 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Haus6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HAUS augmin-like complex subunit 6 N-terminus
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- prostate cancer
- non-insulin-dependent diabetes mellitus
- epithelial basal cell carcinoma
- prostatic carcinoma
- coronary artery disease
role in cell
- assembly
- misalignment
- misalignment in
- cycling
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- cytosol
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Haus6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- spindle assembly
- centrosome cycle
- regulation of microtubule nucleation
- microtubule cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytosol
- HAUS complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding