Ints10 Gene Summary [Mouse]

Predicted to be involved in snRNA processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and spinal cord. Orthologous to human INTS10 (integrator complex subunit 10). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ints10
Official Name
integrator complex subunit 10 [Source:MGI Symbol;Acc:MGI:1918135]
Ensembl ID
ENSMUSG00000031864
Bio databases IDs NCBI: 70885 Ensembl: ENSMUSG00000031864
Aliases integrator complex subunit 10
Synonyms 4921521J11Rik, C8orf35, INT10, integrator complex subunit 10, LOC120097514, RGD1304711
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ints10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast carcinoma
regulated by
  • lipopolysaccharide
  • CST5

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ints10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • snRNA processing
  • regulation of transcription elongation from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleoplasm
  • integrator complex

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.