Crygs Gene Summary [Mouse]

A structural constituent of eye lens. Acts upstream of or within lens development in camera-type eye and morphogenesis of an epithelium. Is expressed in alimentary system; eye; and genitourinary system. Used to study cataract 20 multiple types. Human ortholog(s) of this gene implicated in cataract 20 multiple types. Orthologous to human CRYGS (crystallin gamma S). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Crygs
Official Name
crystallin, gamma S [Source:MGI Symbol;Acc:MGI:1298216]
Ensembl ID
ENSMUSG00000033501
Bio databases IDs NCBI: 12970 Ensembl: ENSMUSG00000033501
Aliases crystallin, gamma S
Synonyms CRYG8, crystallin gamma S, crystallin, gamma S, crystallin γ S, crystallin, γ S, CTRCT20, LOC681467, Opj, rncat
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Crygs often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of eye lens
  • protein binding
  • Beta/Gamma crystallin

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • retinitis pigmentosa
  • multiple types cataract 20
  • pseudoaphakia
  • congenital cataract
regulated by
role in cell
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Crygs gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • morphogenesis of an epithelium
  • lens development in camera-type eye
  • visual perception

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural constituent of eye lens

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.