Engase Gene Summary [Mouse]
Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Acts upstream of or within protein deglycosylation. Predicted to be located in cytosol. Orthologous to human ENGASE (endo-beta-N-acetylglucosaminidase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Engase |
| Official Name | endo-beta-N-acetylglucosaminidase [Source:MGI Symbol;Acc:MGI:2443788] |
| Ensembl ID | ENSMUSG00000033857 |
| Bio databases IDs | |
| Aliases | endo-beta-N-acetylglucosaminidase |
| Synonyms | C130099A03, D230014K01Rik, endo-beta-N-acetylglucosaminidase, endo-β-N-acetylglucosaminidase, RGD1310868 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Engase often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
- glycosidase
- GH18_chitinase-like
- enzyme
- Glycosyl hydrolase family 85
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Engase gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein deglycosylation
- protein folding
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
- hydrolase activity, hydrolyzing O-glycosyl compounds