Capn2

Enables calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to amino acid stimulus; protein catabolic process at postsynapse; and synaptic vesicle endocytosis. Acts upstream of or within blastocyst development and myoblast fusion. Located in several cellular components, including chromatin; cytosol; and lysosome. Is active in postsynapse. Is expressed in several structures, including central nervous system; lens epithelium; molar; oral region epithelium; and skin. Orthologous to human CAPN2 (calpain 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Capn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Capn2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Capn2 gene, providing context for its role in the cell.