Tesk2 Gene Summary [Mouse]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including focal adhesion assembly; protein phosphorylation; and spermatogenesis. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human TESK2 (testis associated actin remodelling kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tesk2 |
| Official Name | testis-specific kinase 2 [Source:MGI Symbol;Acc:MGI:2385204] |
| Ensembl ID | ENSMUSG00000033985 |
| Bio databases IDs | |
| Aliases | testis-specific kinase 2 |
| Synonyms | testis associated actin remodelling kinase 2, testis-specific kinase 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tesk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- protein kinase
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- catalytic domain
- protein binding
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tesk2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- protein phosphorylation
- focal adhesion assembly
- actin cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein tyrosine kinase activity
- protein binding
- protein serine/threonine/tyrosine kinase activity
- metal ion binding
- protein kinase activity
- protein serine/threonine kinase activity