Hid1 Gene Summary [Mouse]

Acts upstream of or within several processes, including insulin processing; secretory granule maturation; and vacuole fusion, non-autophagic. Predicted to be located in cytoplasmic microtubule; cytoplasmic side of Golgi membrane; and cytosol. Predicted to be active in Golgi medial cisterna; Golgi trans cisterna; and membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 105. Orthologous to human HID1 (HID1 domain containing). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hid1
Official Name
HID1 domain containing [Source:MGI Symbol;Acc:MGI:2445087]
Ensembl ID
ENSMUSG00000034586
Bio databases IDs NCBI: 217310 Ensembl: ENSMUSG00000034586
Aliases HID1 domain containing
Synonyms 17orf28, C17orf28, C630004H02Rik, DEE105, DMC1, HID1 domain containing, RGD1311422
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hid1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • High-temperature-induced dauer-formation protein
  • Dyggve-Melchior-Clausen syndrome protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hereditary disorder
  • developmental and epileptic encephalopathy 105 with hypopituitarism
  • infection by HIV-1
regulated by
  • TNF
  • VEGF
  • histamine
  • PF-3893787
  • mir-34 (includes others)
  • HuH7 cells
  • AGRN
regulates
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Cytoplasm
  • cellular membrane
  • Golgi Apparatus
  • cytosol
  • cytoplasmic microtubule
  • Golgi cisternae

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Hid1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • cytoplasm
  • membrane
  • cytosol
  • Golgi apparatus
  • Golgi trans cisterna
  • cytoplasmic microtubule
  • Golgi medial cisterna

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.