Ppp1r21 Gene Summary [Mouse]

Predicted to enable RNA binding activity. Predicted to be active in early endosome. Is expressed in nervous system; neural retina; and thymus primordium. Orthologous to human PPP1R21 (protein phosphatase 1 regulatory subunit 21). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ppp1r21
Official Name
protein phosphatase 1, regulatory subunit 21 [Source:MGI Symbol;Acc:MGI:1921075]
Ensembl ID
ENSMUSG00000034709
Bio databases IDs NCBI: 73825 Ensembl: ENSMUSG00000034709
Aliases protein phosphatase 1, regulatory subunit 21
Synonyms 1110018J12Rik, CCDC128, FERRY2, Fy-2, KLRAQ1, NEDHFBA, protein phosphatase 1 regulatory subunit 21, protein phosphatase 1, regulatory subunit 21, RGD1565310
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp1r21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Predicted coiled-coil domain-containing protein
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neurodevelopmental disorder with hypotonia, facial dysmorphism, and brain abnormalities
  • hereditary disorder
  • colorectal cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • early endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp1r21 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.