Rnf38 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in nucleoplasm and sperm flagellum. Is expressed in central nervous system; dorsal root ganglion; heart; limb; and sensory organ. Orthologous to human RNF38 (ring finger protein 38). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rnf38 |
| Official Name | ring finger protein 38 [Source:MGI Symbol;Acc:MGI:1920719] |
| Ensembl ID | ENSMUSG00000035696 |
| Bio databases IDs | |
| Aliases | ring finger protein 38 |
| Synonyms | 1700065B19Rik, 2610202O07Rik, FLJ21813, OIP1, ring finger protein 38 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf38 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin protein ligase activity
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- enzyme
- Ring finger domain
- protein binding
- RING-like zinc finger
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rnf38 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- male gonad development
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- sperm flagellum
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding